CAS No. 22881-35-2

Batch: Purity:98
Famprofazone Chemical Structure
Chemical Structure
Check the Famprofazone product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 22881-35-2
Molecular Formula

C24H31N3O

Molecular Weight (MW) 377.52
SMILES CC(C)C1=C(N(N(C1=O)C2=CC=CC=C2)C)CN(C)C(C)CC3=CC=CC=C3

Biological Activity

Famprofazone is a non-steroidal anti-inflammatory drug belonging to the pyrazolone class that functions as an analgesic and antipyretic agent. It inhibits cyclooxygenase-mediated prostaglandin synthesis to reduce inflammation, fever, and pain perception. In vivo studies demonstrate that famprofazone undergoes metabolic conversion to methamphetamine and amphetamine, which contributes to its central pharmacological effects and overall therapeutic profile.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Ethanol 12 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
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Note: Technical data last updated: Sep 1, 2026.