CAS No. 1593673-23-4
Batch:
Purity:99.77
Chemical Structure
Check the
Etripamil
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1593673-23-4 | |
|---|---|---|
| Molecular Formula |
C₂₇H₃₆N₂O₄ |
|
| Molecular Weight (MW) | 452.59 |
Etripamil (MSP-2017) is a short-acting L-type calcium channel antagonist that targets slow L-type calcium channels in atrioventricular (AV) nodal cells. By inhibiting trans-sarcolemmal calcium influx through L-type calcium channels, etripamil slows AV nodal conduction velocity and prolongs the AV nodal refractory period. This transient electrophysiological action disrupts AV node-dependent reentrant pathways, resulting in rapid prolongation of the PR interval and suppression of supraventricular tachyarrhythmias.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
91 mg/mL
(201.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 91 mg/mL |
| Ethanol | 91 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.