CAS No. 54350-48-0
Batch:
Purity:99.06
Chemical Structure
Check the
Etretinate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 54350-48-0 | |
|---|---|---|
| Molecular Formula |
C23H30O3 |
|
| Molecular Weight (MW) | 354.48 | |
| SMILES | CCOC(=O)C=C(C)C=CC=C(C)C=CC1=C(C(=C(C=C1C)OC)C)C |
Etretinate is an oral aromatic retinoid that functions as an agonist of retinoic acid receptors. By activating retinoid receptor signaling pathways, etretinate regulates target gene expression involved in cellular growth and epidermal homeostasis. Downstream cellular responses include the induction of cell differentiation, the inhibition of cell proliferation, and the attenuation of tissue infiltration by inflammatory cells.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
70 mg/mL
(197.47 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 70 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.