Etomoxir sodium salt Mechanism of Action: CPT1A Inhibition in Cancer Cell Research

Etomoxir sodium salt MOA:Targeting CPT1A/Fatty Acid Oxidation for Cancer Metabolism and Tumor Microenvironment

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Etomoxir sodium salt is an irreversible carnitine palmitoyltransferase 1 (CPT1) inhibitor. It affects mTOR, AMPK, and NF-κB signaling pathways by blocking acylcarnitine entry into mitochondria and inhibiting mitochondrial fatty acid β-oxidation, effectively suppressing tumor cell proliferation, metastasis, and immune cell survival, while promoting apoptosis.

Primary Applications and Mechanism of Action