Etomidate hydrochloride

For research use only.

Catalog No.S4724 Synonyms: Amidate, R16659 hydrochloride

Etomidate hydrochloride Chemical Structure

CAS No. 53188-20-8

Etomidate (Amidate, R 16659) hydrochloride is a general anesthetic that produces its effects by enhancing GABA(A) receptor activity.

Purity & Quality Control

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Biological Activity

Description Etomidate (Amidate, R 16659) hydrochloride is a general anesthetic that produces its effects by enhancing GABA(A) receptor activity.
Targets
GABA(A) receptor [1]
()

Protocol

Solubility (25°C)

In vitro DMSO 56 mg/mL (199.46 mM)
Water 56 mg/mL (199.46 mM)
Ethanol ''56 mg/mL

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 280.75
Formula

C14H17ClN2O2

CAS No. 53188-20-8
Storage powder
in solvent
Synonyms Amidate, R16659 hydrochloride

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
Dosage mg/kg Average weight of animals g Dosing volume per animal ul Number of animals
Step 2: Enter the in vivo formulation ()
% DMSO % % Tween 80 % ddH2O
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Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass
    Concentration
    Volume
    Molecular Weight

*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and SDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

  • C1
    V1
    C2
    V2

* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / COA (available online).

The Serial Dilution Calculator Equation

  • Serial Dilutions

  • Computed Result

  • C1=C0/X C1: LOG(C1):
    C2=C1/X C2: LOG(C2):
    C3=C2/X C3: LOG(C3):
    C4=C3/X C4: LOG(C4):
    C5=C4/X C5: LOG(C5):
    C6=C5/X C6: LOG(C6):
    C7=C6/X C7: LOG(C7):
    C8=C7/X C8: LOG(C8):
Molecular Weight Calculator

Molecular Weight Calculator

Enter the chemical formula of a compound to calculate its molar mass and elemental composition:

Total Molecular Weight: g/mol

Tip: Chemical formula is case sensitive. C10H16N2O2 c10h16n2o2

Instructions to calculate molar mass (molecular weight) of a chemical compound:

To calculate molar mass of a chemical compound, please enter its chemical formula and click 'Calculate'.

Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03240055 Completed Drug: spinal anesthesia|Other: etomidate Dose-Response Relationship Drug General Hospital of Ningxia Medical University June 1 2017 Not Applicable
NCT02174120 Unknown status Drug: propofol|Drug: etomidate Target Controlled Infusion|General Anesthesia Henan Provincial People''s Hospital October 2014 Phase 4
NCT02208596 Unknown status Drug: pentazocine|Drug: propofol|Drug: Etomidate Induced Abortion|Anesthesia Third Affiliated Hospital of Zhengzhou University September 2014 Phase 4
NCT01792037 Completed Drug: Etomidate|Drug: Midazolam|Drug: methylprednisolone Adrenocortical Deficiency|Hemodynamic Instability Istanbul University December 2012 Phase 4
NCT00862381 Completed Drug: Hydrocortisone|Drug: Placebo Patient Admitted in Reanimation University Hospital Grenoble October 2008 Phase 3

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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GABA Receptor Signaling Pathway Map

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID