CAS No. 1099-45-2

Batch: Purity:98
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Ethyl (triphenylphosphoranylidene) acetate Chemical Structure
Chemical Structure
Check the Ethyl (triphenylphosphoranylidene) acetate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name ethyl 2-(triphenyl-λ5-phosphanylidene)acetate
CAS Number 1099-45-2
Molecular Formula

C22H21O2P
Molecular Weight (MW) 348.37
SMILES CCOC(=O)C=P(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3
InChIKey IIHPVYJPDKJYOU-UHFFFAOYSA-N

Ordering Information

Biological Activity

Ethyl (triphenylphosphoranylidene) acetate acts as a cholinesterase inhibitor that targets acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). By inhibiting these cholinesterase enzymes, the compound prevents the hydrolysis of acetylcholine within the cholinergic signaling pathway. This inhibition elevates local acetylcholine concentrations, leading to enhanced neurotransmission and modulating downstream cholinergic phenotypes associated with enzyme inhibition. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 69 mg/mL (198.06 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.