CAS No. 617-35-6

Batch: Purity:
Ethyl pyruvate Chemical Structure
Chemical Structure
Check the Ethyl pyruvate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 617-35-6
Molecular Formula

C5H8O3
Molecular Weight (MW) 116.12
SMILES CCOC(=O)C(=O)C

Biological Activity

Ethyl pyruvate is an aliphatic ester of pyruvic acid with anti-inflammatory, anti-oxidative, and neuroprotective properties. It suppresses pro-inflammatory cytokine release and attenuates reactive oxygen species generation, primarily through the inhibition of NF-kB activation and HMGB1 secretion. Downstream, ethyl pyruvate prevents apoptotic cell death and mitigates oxidative cell injury, demonstrating broad protective effects in models of systemic inflammation and neuronal damage.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.