CAS No. 831-61-8

Batch: Purity:99.05
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Ethyl gallate Chemical Structure
Chemical Structure
Check the Ethyl gallate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 831-61-8
Molecular Formula

C9H10O5
Molecular Weight (MW) 198.17
SMILES CCOC(=O)C1=CC(=C(C(=C1)O)O)O

Biological Activity

Ethyl gallate is a naturally occurring phenolic compound and food additive with antimicrobial and pro-apoptotic activities. It activates the death receptor-dependent pathway of apoptosis by increasing the expression of caspase-3, caspase-8, and caspase-9, while promoting cleavage of Bid. This cascade triggers downstream caspase activation and mitochondrial apoptotic signaling, ultimately suppressing cellular proliferation and inducing programmed cell death.

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 39 mg/mL (196.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.