CAS No. 59-06-3

Batch: Purity:99.22
Ethopabate Chemical Structure
Chemical Structure
Check the Ethopabate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name methyl 4-acetamido-2-ethoxybenzoate
CAS Number 59-06-3
Molecular Formula

C12H15NO4

Molecular Weight (MW) 237.25
SMILES CCOC1=C(C=CC(=C1)NC(=O)C)C(=O)OC
InChIKey GOVWOKSKFSBNGD-UHFFFAOYSA-N

Ordering Information

Biological Activity

Ethopabate is a synthetic antiprotozoal agent and coccidiostat that acts as a competitive inhibitor of the folate synthesis pathway in parasite species. By competing with p-aminobenzoic acid, ethopabate interrupts dihydropteroate synthesis, thereby disrupting nucleic acid biosynthesis and inhibiting parasite replication. It exhibits potent activity against Eimeria species, effectively suppressing intestinal lesions, oocyst shedding, and mortality associated with avian coccidiosis.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 47 mg/mL (198.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 47 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.