CAS No. 1264-62-6

Batch: Purity:97
Erythromycin Ethylsuccinate Chemical Structure
Chemical Structure
Check the Erythromycin Ethylsuccinate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 1264-62-6
Molecular Formula

C43H75NO16 

Molecular Weight (MW) 862.05
SMILES CCC1C(C(C(C(=O)C(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)OC(=O)CCC(=O)OCC)(C)O)C)C)O)(C)O

Ordering Information

Biological Activity

Erythromycin Ethylsuccinate is an oral macrolide antibiotic that targets the bacterial 50S ribosomal subunit. By reversibly binding to the 50S ribosome, it blocks peptide bond formation and inhibits translocation during protein translation. This inhibition disrupts bacterial protein synthesis, leading to the suppression of bacterial growth and proliferation across susceptible Gram-positive and select Gram-negative organisms. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 172 mg/mL (199.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 172 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.