CAS No. 1210344-83-4
Batch:
Purity:99.85
Chemical Structure
Check the
Ertugliflozin L-pyroglutamic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (1S,2S,3S,4R,5S)-5-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-1-(hydroxymethyl)-6,8-dioxabicyclo[3.2.1]octane-2,3,4-triol;(2S)-5-oxopyrrolidine-2-carboxylic acid | |
|---|---|---|
| CAS Number | 1210344-83-4 | |
| Molecular Formula |
C27H32ClNO10 |
|
| Molecular Weight (MW) | 566 | |
| SMILES | CCOC1=CC=C(CC2=C(Cl)C=CC(=C2)C34OCC(CO)(O3)C(O)C(O)C4O)C=C1.OC(=O)C5CCC(=O)N5 | |
| InChIKey | YHIUPZFKHZTLSH-LXYIGGQGSA-N |
Ertugliflozin L-pyroglutamic acid is a potent, selective, and orally active inhibitor of human sodium-dependent glucose cotransporter 2 (h-SGLT2) with an IC50 of. By blocking SGLT2 in renal proximal tubules, it reduces renal glucose reabsorption and promotes urinary glucose excretion. This mechanism lowers systemic blood glucose levels without stimulating insulin secretion, supporting its therapeutic potential in type 2 diabetes mellitus. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(176.67 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | 10 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Ertugliflozin L-pyroglutamic acid Clinical Trials
- Ertugliflozin L-pyroglutamic acid Solubility in DMSO
- Ertugliflozin L-pyroglutamic acid Stock Solution
- Ertugliflozin L-pyroglutamic acid Storage
- Ertugliflozin L-pyroglutamic acid Stability
- Ertugliflozin L-pyroglutamic acid Molecular Weight
- Ertugliflozin L-pyroglutamic acid SMILES
- Ertugliflozin L-pyroglutamic acid Chemical Structure (2D and 3D)
- Ertugliflozin L-pyroglutamic acid SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.