CAS No. 95041-90-0

Batch: Purity:99.86
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Erianin Chemical Structure
Chemical Structure
Check the Erianin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name 2-methoxy-5-[2-(3,4,5-trimethoxyphenyl)ethyl]phenol
CAS Number 95041-90-0
Molecular Formula

C18H22O5
Molecular Weight (MW) 318.36
SMILES COC1=C(C=C(C=C1)CCC2=CC(=C(C(=C2)OC)OC)OC)O
InChIKey UXDFUVFNIAJEGM-UHFFFAOYSA-N

Biological Activity

Erianin is a natural bibenzyl compound derived from Dendrobium chrysotoxum that acts as a potent inhibitor of tumor angiogenesis and endothelial cell growth. It suppresses indoleamine 2,3-dioxygenase (IDO)-induced angiogenesis and modulates downstream signaling, including the STAT3 pathway, to disrupt capillary tube formation and induce apoptosis in endothelial and tumor cells. Consequently, Erianin suppresses tumor growth and neovascularization both in vitro and in vivo. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 63 mg/mL (197.88 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Reference

[1] Br Dent J. 2004;196(12):735-735.

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Note: Technical data last updated: Sep 1, 2026.