CAS No. 84611-23-4
Batch:
Purity:99.97
Chemical Structure
Check the
Erdosteine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid | |
|---|---|---|
| CAS Number | 84611-23-4 | |
| Molecular Formula |
C8H11NO4S2 |
|
| Molecular Weight (MW) | 249.31 | |
| SMILES | C1CSC(=O)C1NC(=O)CSCC(=O)O | |
| InChIKey | QGFORSXNKQLDNO-UHFFFAOYSA-N |
Biological Activity
Erdosteine is a mucolytic expectorant that inhibits lipopolysaccharide (LPS)-induced NF-κB activation. Following metabolic conversion to active thiol-containing metabolites, it exhibits free radical scavenging and mucolytic activities. By suppressing NF-κB signaling and regulating mucus production, erdosteine decreases mucus viscosity and increases mucociliary clearance, thereby facilitating airway clearance and protecting against oxidative tissue damage.
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
50 mg/mL
(200.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 10 mg/mL |
| Water | Insoluble |
| DMSO |
50 mg/mL
(200.55 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 10 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
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Note: Technical data last updated: Sep 1, 2026.