CAS No. 123997-26-2

Batch: Purity:99.47
Eprinomectin Chemical Structure
Chemical Structure
Check the Eprinomectin product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name N-[(2S,3R,4R,6S)-6-[(2S,3R,4S,6R)-6-[(1'R,2R,3S,4'S,6S,8'R,10'Z,12'S,13'S,14'Z,16'Z,20'R,21'R,24'S)-21',24'-dihydroxy-3,11',13',22'-tetramethyl-2'-oxo-2-propan-2-ylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-12'-yl]oxy-4-methoxy-2-methyloxan-3-yl]oxy-4-methoxy-2-methyloxan-3-yl]acetamide
CAS Number 123997-26-2
Molecular Formula

'--

InChIKey WPNHOHPRXXCPRA-TVXIRPTOSA-N

Ordering Information

Biological Activity

Eprinomectin is a broad-spectrum macrocyclic lactone endectocide that selectively targets glutamate-gated chloride channel receptors in invertebrate nerve and muscle tissues. Activation of these channels increases neuronal membrane permeability to chloride ions, inducing cellular hyperpolarization. This mechanistic pathway disrupts signal transmission within the central nervous system, producing neuromuscular paralysis and demonstrating broad-spectrum anthelmintic, insecticidal, and miticidal activities against various parasitic species.

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
Ethanol 100 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.