CAS No. 110623-72-8
Batch:
Purity:99.91
Chemical Structure
Check the
Epimedin A
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 110623-72-8 | |
|---|---|---|
| Molecular Formula |
C39H50O20 |
|
| Molecular Weight (MW) | 838.80 | |
| SMILES | COC1=CC=C(C=C1)C2=C(OC3OC(C)C(O)C(O)C3OC4OC(CO)C(O)C(O)C4O)C(=O)C5=C(O)C=C(OC6OC(CO)C(O)C(O)C6O)C(=C5O2)CC=C(C)C |
Epimedin A is a bioactive flavonoid glycoside isolated from Herba Epimedii with osteogenic, anti-inflammatory, and antioxidant properties. It modulates bone metabolism by promoting osteoblast differentiation and matrix mineralization through activation of Wnt/β-catenin signaling. Furthermore, Epimedin A suppresses inflammatory responses and inhibits bone resorption by downregulating the NF-κB pathway, contributing to enhanced bone tissue homeostasis.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(119.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 50 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.