CAS No. 27503-81-7
Batch:
Purity:98.95
Chemical Structure
Check the
Ensulizole
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 27503-81-7 | |
|---|---|---|
| Molecular Formula |
C13H10N2O3S |
|
| Molecular Weight (MW) | 274.30 | |
| SMILES | O[S](=O)(=O)C1=CC2=C(C=C1)N=C([NH]2)C3=CC=CC=C3 |
Ensulizole (PBSA) is a water-soluble sulfonated UV absorber that functions as a sunscreen ingredient by providing intense UVB and partial UVA protection. Upon exposure to UV or sunlight irradiation, ensulizole acts as a photosensitizer that generates reactive oxygen species (ROS). This induced oxidative stress subsequently promotes DNA strand breaks and oxidative DNA damage in exposed cells. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
5 mg/mL
(18.22 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.