CAS No. 1370468-36-2
Batch:
Purity:99.66
Chemical Structure
Check the
Elbasvir
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 1370468-36-2 | |
|---|---|---|
| Molecular Formula |
C49H55N9O7 |
|
| Molecular Weight (MW) | 882.02 | |
| SMILES | CC(C)C(C(=O)N1CCCC1C2=NC=C(N2)C3=CC4=C(C=C3)N5C(OC6=C(C5=C4)C=CC(=C6)C7=CN=C(N7)C8CCCN8C(=O)C(C(C)C)NC(=O)OC)C9=CC=CC=C9)NC(=O)OC |
Elbasvir (MK8742) is a potent hepatitis C virus (HCV) NS5A inhibitor with median EC50 values ranging from 0.2 tool/L across various viral genotypes. By targeting the NS5A protein, it disrupts both HCV RNA replication and virion assembly. This selective inhibition suppresses viral polyprotein processing and replication complex formation, thereby impairing viral propagation in infected host cells. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(113.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(113.37 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.