CAS No. 3258-02-4
Batch:
Purity:99.73
Chemical Structure
Check the
EIDD-1931 (NHC)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-4-(hydroxyamino)pyrimidin-2-one | |
|---|---|---|
| CAS Number | 3258-02-4 | |
| Molecular Formula |
C9H13N3O6 |
|
| Molecular Weight (MW) | 259.22 | |
| SMILES | OCC1OC(C(O)C1O)N2C=C\C(NC2=O)=N\O | |
| InChIKey | XCUAIINAJCDIPM-XVFCMESISA-N |
EIDD-1931 (NHC) is a broad-spectrum antiviral ribonucleoside analog that targets viral RNA-dependent RNA polymerase (RdRp). It demonstrates potent activity against SARS-CoV-2, MERS-CoV, and SARS-CoV with an average IC50 of. Upon incorporation into nascent viral RNA, EIDD-1931 induces lethal RNA mutagenesis, effectively suppressing viral replication and retaining full potency against remdesivir-resistant coronavirus strains. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 15 mg/mL |
| Ethanol | 3 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.