CAS No. 608-66-2
Batch:
Purity:98
Chemical Structure
Check the
Dulcitol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 608-66-2 | |
|---|---|---|
| Molecular Formula |
C6H14O6 |
|
| Molecular Weight (MW) | 182.17 | |
| SMILES | C(C(C(C(C(CO)O)O)O)O)O |
Dulcitol (Galactitol) is a naturally occurring sugar alcohol produced through the reduction of galactose by aldose reductase. Intracellular accumulation of dulcitol drives hyperosmotic stress and cell swelling within the polyol pathway. Elevated dulcitol levels impair membrane integrity and disrupt cellular metabolic homeostasis, contributing to cataract development and lens fiber cell damage associated with galactosemia.
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 36 mg/mL |
| DMSO |
6 mg/mL
(32.93 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.