GSK1349572 (Dolutegravir) IC50 for Cell-based and Cell-free Assays

Comprehensive IC50 Values for GSK1349572 (Dolutegravir) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.

GSK1349572 (Dolutegravir) is a potent metal-chelating HIV-1 integrase inhibitor. It affects HIV-1 integration and inflammatory signaling pathways, by binding to the catalytic domain and chelating metal ions, to inhibit viral DNA strand transfer and HIV-1 replication.

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