CAS No. 97-39-2
Batch:
Purity:99.79
Chemical Structure
Check the
Ditolylguanidine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 97-39-2 | |
|---|---|---|
| Molecular Formula |
C15H17N3 |
|
| Molecular Weight (MW) | 239.32 |
Ditolylguanidine is a non-selective agonist of sigma receptors that binds with high affinity to both σ1 and σ2 receptor subtypes. Upon activation of sigma receptors, it modulates intracellular signaling cascades and cellular proliferation. It effectively inhibits the growth of small cell lung cancer cells, making it a valuable tool for investigating sigma receptor function and lung cancer biology. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
48 mg/mL
(200.56 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 12 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.