CAS No. 147-20-6
Batch:
Purity:95.88
Chemical Structure
Check the
Diphenylpyraline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 147-20-6 | |
|---|---|---|
| Molecular Formula |
C19H23NO |
|
| Molecular Weight (MW) | 281.39 |
Diphenylpyraline is a first-generation antihistamine that acts as a histamine H1 receptor antagonist. By blocking histamine H1 receptor signaling, it suppresses allergic responses and downstream inflammatory pathways. In addition, diphenylpyraline interacts with the dopamine transporter system, inhibiting dopamine reuptake and demonstrating potential utility in research on substance abuse and addiction mechanisms. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
56 mg/mL
(199.01 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 56 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.