CAS No. 132-18-3
Batch:
Purity:99.95
Chemical Structure
Check the
Diphenylpyraline hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-benzhydryloxy-1-methylpiperidine;hydrochloride | |
|---|---|---|
| CAS Number | 132-18-3 | |
| Molecular Formula |
C19H24ClNO |
|
| Molecular Weight (MW) | 317.85 | |
| SMILES | CN1CCC(CC1)OC(C2=CC=CC=C2)C3=CC=CC=C3.Cl | |
| InChIKey | LPRLDRXGWKXRMQ-UHFFFAOYSA-N |
Diphenylpyraline hydrochloride is a first-generation antihistamine that acts as a histamine H1 receptor antagonist. By selectively blocking histamine H1 receptors, it inhibits histamine-mediated activation of the phospholipase C pathway and intracellular calcium mobilization. This blockade suppresses downstream allergic inflammatory cascades, vascular permeability, and smooth muscle contraction associated with allergic responses. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
63 mg/mL
(198.2 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Diphenylpyraline hydrochloride Solubility in DMSO
- Diphenylpyraline hydrochloride Stock Solution
- Diphenylpyraline hydrochloride Storage
- Diphenylpyraline hydrochloride Stability
- Diphenylpyraline hydrochloride Molecular Weight
- Diphenylpyraline hydrochloride SMILES
- Diphenylpyraline hydrochloride Chemical Structure (2D and 3D)
- Diphenylpyraline hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.