CAS No. 106-65-0
Chemical Structure
Check the
Dimethyl succinate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| CAS Number | 106-65-0 | |
|---|---|---|
| Molecular Formula |
C6H10O4 |
|
| Molecular Weight (MW) | 146.14 |
Biological Activity
Dimethyl succinate is a cell-permeable succinate derivative that acts as a metabolic precursor. It elevates intracellular succinate levels, driving mitochondrial complex I reverse electron transport and reactive oxygen species generation. This metabolic alteration leads to the stabilization of hypoxia-inducible factor-1α (HIF-1α) and promotes downstream pro-inflammatory responses, including enhanced expression of interleukin-1β. [1]
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Note: Technical data last updated: Sep 1, 2026.