CAS No. 199926-38-0

Batch: Purity:99.92
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Dihydroxyfumaric acid hydrate Chemical Structure
Chemical Structure
Check the Dihydroxyfumaric acid hydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 199926-38-0
Molecular Formula

C4H6O7
Molecular Weight (MW) 166.09
SMILES O.OC(=O)C(/O)=C(\O)C(O)=O

Ordering Information

Biological Activity

Dihydroxyfumaric acid hydrate is an endogenous metabolite that acts as a free radical generator through auto-oxidation. Upon oxidation, dihydroxyfumaric acid produces superoxide radicals and hydrogen peroxide, modulating intracellular redox status and oxidative stress pathways. This generation of reactive oxygen species subsequently influences downstream cellular responses, including lipid peroxidation and redox-sensitive signaling cascades. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 33 mg/mL (198.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 33 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.