CAS No. 587-63-3
Batch:
Purity:99.97
Chemical Structure
Check the
7,8-dihydrokawain
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 587-63-3 | |
|---|---|---|
| Molecular Formula |
C14H16O3 |
|
| Molecular Weight (MW) | 232.28 |
7,8-Dihydrokawain is a naturally occurring kavalactone that functions as a modulator of central nervous system pathways and inflammatory responses. It inhibits NF-kB activation, resulting in the downregulation of pro-inflammatory cytokine expression and attenuated inflammatory signaling. Additionally, 7,8-dihydrokawain modulates neurotransmitter systems to mediate sedative and anxiolytic phenotypes, offering potential therapeutic utility in stress, anxiety, and sleep disorders. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
46 mg/mL
(198.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 46 mg/mL |
| Water | Insoluble |
| DMSO |
46 mg/mL
(198.03 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.