CAS No. 33564-31-7
Batch:
Purity:99.11
Chemical Structure
Check the
Diflorasone diacetate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 33564-31-7 | |
|---|---|---|
| Molecular Formula |
C26H32F2O7 |
|
| Molecular Weight (MW) | 494.53 |
Diflorasone diacetate is a synthetic corticosteroid anti-inflammatory agent that acts as a glucocorticoid receptor agonist. Upon binding, it suppresses pro-inflammatory mediator release and downstream signaling cascades, inhibiting inflammatory cell infiltration and cutaneous edema. This suppression of inflammatory pathways attenuates localized hypersensitivity responses, providing potent activity against allergic and inflammatory skin conditions such as dermatitis. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
99 mg/mL
(200.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
99 mg/mL
(200.19 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.