CAS No. 1609-47-8
Chemical Structure
Check the
Diethyl Pyrocarbonate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | ethoxycarbonyl ethyl carbonate | |
|---|---|---|
| CAS Number | 1609-47-8 | |
| Molecular Formula |
C6H10O5 |
|
| Molecular Weight (MW) | 162.14 | |
| InChIKey | FFYPMLJYZAEMQB-UHFFFAOYSA-N |
Diethyl pyrocarbonate is a non-specific inhibitor of ribonuclease (RNase) that acts as a chemical modifying agent relatively selective for the imidazole group of histidine residues. By covalently modifying histidine, serine, threonine, and tyrosine side chains, it disrupts enzymatic active sites and suppresses central CO2 chemosensitivity, resulting in structural conformational changes and inactivation of nucleases like RNase A.[1][2]
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Note: Technical data last updated: Sep 1, 2026.