CAS No. 97-23-4
Batch:
Purity:99.09
Chemical Structure
Check the
Dichlorophen
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | 4-chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol | |
|---|---|---|
| CAS Number | 97-23-4 | |
| Molecular Formula |
C13H10Cl2O2 |
|
| Molecular Weight (MW) | 269.12 | |
| SMILES | C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O | |
| InChIKey | MDNWOSOZYLHTCG-UHFFFAOYSA-N |
Biological Activity
Dichlorophen is an antimicrobial, fungicidal, and anticestodal agent that functions primarily by disrupting mitochondrial oxidative phosphorylation. By uncoupling the proton gradient across mitochondrial membranes, it inhibits ATP synthesis and disrupts cellular energy homeostasis. This downstream metabolic dysfunction leads to loss of membrane integrity, accumulation of reactive oxygen species, and the suppression of microbial and parasitic viability. [1]
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
54 mg/mL
(200.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Reference
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Note: Technical data last updated: Sep 1, 2026.