CAS No. 299-88-7
Batch:
Purity:99.88
Chemical Structure
Check the
Dibenzoyl Thiamine
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 299-88-7 | |
|---|---|---|
| Molecular Formula |
C26H26N4O4S |
|
| Molecular Weight (MW) | 490.57 | |
| SMILES | CC1=NC=C(C(=N1)N)CN(C=O)C(=C(CCOC(=O)C2=CC=CC=C2)SC(=O)C3=CC=CC=C3)C |
Dibenzoyl Thiamine (Bentiamine) is a lipophilic synthetic derivative and prodrug of vitamin B1 (thiamine). Upon uptake, it is rapidly converted into free thiamine, which serves as an essential precursor for thiamine diphosphate to regulate thiamine-dependent enzymatic pathways. This lipid-soluble derivative efficiently crosses biological membranes to elevate intracellular thiamine levels, supporting cellular energy metabolism and attenuating thiamine deficiency-associated metabolic dysfunctions. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
98 mg/mL
(199.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.