CAS No. 55-43-6
Batch:
Purity:98
Chemical Structure
Check the
Dibenamine Hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 55-43-6 | |
|---|---|---|
| Molecular Formula |
C16H18ClN.HCl |
|
| Molecular Weight (MW) | 296.23 | |
| SMILES | C1=CC=C(C=C1)CN(CCCl)CC2=CC=CC=C2.Cl |
Dibenamine Hydrochloride is a haloalkylamine derivative that acts as an irreversible antagonist of α1 adrenoceptors. By alkylating α-adrenergic receptors, it inhibits agonist binding and blocks receptor-mediated signalling pathways. This blockade impairs sympathetic neuroeffector transmission and inhibits agonist-induced smooth muscle contraction, leading to vasodilation and suppression of adrenergic responses in vascular tissue. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
59 mg/mL
(199.16 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Dibenamine Hydrochloride Solubility in DMSO
- Dibenamine Hydrochloride Stock Solution
- Dibenamine Hydrochloride Storage
- Dibenamine Hydrochloride Stability
- Dibenamine Hydrochloride Molecular Weight
- Dibenamine Hydrochloride SMILES
- Dibenamine Hydrochloride Chemical Structure (2D and 3D)
- Dibenamine Hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.