CAS No. 2138299-34-8
Batch:
Purity:95.31
Chemical Structure
Check the
diABZI STING agonist-1 trihydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide;trihydrochloride | |
|---|---|---|
| CAS Number | 2138299-34-8 | |
| Molecular Formula |
C42H51N13O7.3ClH |
|
| Molecular Weight (MW) | 959.32 | |
| InChIKey | CKESNWHACHILIV-BILRHTGOSA-N |
diABZI STING agonist-1 trihydrochloride is a selective agonist of human STING and mouse STING (EC. Activation of the STING pathway downstream of receptor binding induces phosphorylation of TBK1 and IRF, driving robust type I interferon secretion, particularly IFN-β, alongside proinflammatory cytokine production. These STING-dependent signals promote CD+ T cell-mediated adaptive immune responses, leading to potent antitumor efficacy in vivo. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(104.24 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- diABZI STING agonist-1 trihydrochloride Solubility in DMSO
- diABZI STING agonist-1 trihydrochloride Stock Solution
- diABZI STING agonist-1 trihydrochloride Storage
- diABZI STING agonist-1 trihydrochloride Stability
- diABZI STING agonist-1 trihydrochloride Molecular Weight
- diABZI STING agonist-1 trihydrochloride Chemical Structure (2D and 3D)
- diABZI STING agonist-1 trihydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.