CAS No. 2138498-18-5
Batch:
Purity:99.86
Chemical Structure
Check the
diABZI STING agonist-1 (tautomerism)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 1-[(E)-4-[5-carbamoyl-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-(3-morpholin-4-ylpropoxy)benzimidazol-1-yl]but-2-enyl]-2-[(2-ethyl-5-methylpyrazole-3-carbonyl)amino]-7-methoxybenzimidazole-5-carboxamide | |
|---|---|---|
| CAS Number | 2138498-18-5 | |
| Molecular Formula |
C42H51N13O7 |
|
| Molecular Weight (MW) | 849.95 | |
| SMILES | CCN1C(=CC(=N1)C)C(=O)NC2=NC3=C(N2CC=CCN4C5=C(C=C(C=C5OCCCN6CCOCC6)C(=O)N)N=C4NC(=O)C7=CC(=NN7CC)C)C(=CC(=C3)C(=O)N)OC | |
| InChIKey | JGLMVXWAHNTPRF-CMDGGOBGSA-N |
diABZI STING agonist-1 is a potent non-nucleotide agonist of stimulator of interferon genes (STING). Activation of STING stimulates downstream TBK1/IRF3 and NF-kB signaling pathways, driving the transcription and release of type I interferons and proinflammatory cytokines. This pathway activation enhances innate immune signaling and promotes systemic antitumor responses in immunocompetent models. [1]
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(117.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(117.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(117.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(117.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
33 mg/mL
(38.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- diABZI STING agonist-1 (tautomerism) Mechanism of Action: STING Activation in Antigen-Presenting Cells Research
- diABZI STING agonist-1 (tautomerism) Working Concentration | Cell Culture | Treatment
- diABZI STING agonist-1 (tautomerism) Solubility in DMSO
- diABZI STING agonist-1 (tautomerism) Stock Solution
- diABZI STING agonist-1 (tautomerism) Storage
- diABZI STING agonist-1 (tautomerism) Stability
- diABZI STING agonist-1 (tautomerism) Combination Database
- diABZI STING agonist-1 (tautomerism) Molecular Weight
- diABZI STING agonist-1 (tautomerism) SMILES
- diABZI STING agonist-1 (tautomerism) Chemical Structure (2D and 3D)
- diABZI STING agonist-1 (tautomerism) IC50 for Cell-based and Cell-free Assays
- diABZI STING agonist-1 (tautomerism) Sigma (bl3h9a6eeb18)? Try a better option.
- diABZI STING agonist-1 (tautomerism) MedChemExpress (HY-112921B)? Try a better option.
- diABZI STING agonist-1 (tautomerism) Cayman (28054)? Try a better option.
- diABZI STING agonist-1 (tautomerism) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.