CAS No. 386750-22-7
| IUPAC Name | butanedioic acid;4-[2-(dimethylamino)-1-(1-hydroxycyclohexyl)ethyl]phenol;hydrate | |
|---|---|---|
| CAS Number | 386750-22-7 | |
| Molecular Formula |
C16H25NO2.C4H6O4.H2O |
|
| Molecular Weight (MW) | 399.48 | |
| SMILES | CN(C)CC(C1=CC=C(C=C1)O)C2(CCCCC2)O.C(CC(=O)O)C(=O)O.O | |
| InChIKey | PWPDEXVGKDEKTE-UHFFFAOYSA-N |
Desvenlafaxine Succinate hydrate is a serotonin and norepinephrine reuptake inhibitor targeting the serotonin transporter (Ki = 40.2 nM) and norepinephrine transporter (Ki = 558.4 nM). By blocking the reuptake of serotonin and norepinephrine, it elevates extracellular neurotransmitter concentrations in the central nervous system. This enhancement of monoaminergic neurotransmission modulates downstream neural signaling pathways to exert antidepressant and analgesic phenotypes in preclinical models. [1]
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Concentration
Volume
Mass
|
|---|
| Solvent | Solubility & Note |
|---|---|
| DMSO |
80 mg/mL
(200.26 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
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- Desvenlafaxine Succinate hydrate Solubility in DMSO
- Desvenlafaxine Succinate hydrate Stock Solution
- Desvenlafaxine Succinate hydrate Storage
- Desvenlafaxine Succinate hydrate Stability
- Desvenlafaxine Succinate hydrate Molecular Weight
- Desvenlafaxine Succinate hydrate SMILES
- Desvenlafaxine Succinate hydrate Chemical Structure (2D and 3D)
- Desvenlafaxine Succinate hydrate SDS｜MSDS