CAS No. 51481-10-8
Batch:
Purity:99.7382
Chemical Structure
Check the
Deoxynivalenol
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | (1R,2R,3S,7R,9R,10R,12S)-3,10-dihydroxy-2-(hydroxymethyl)-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-4-one | |
|---|---|---|
| CAS Number | 51481-10-8 | |
| Molecular Formula |
C15H20O6 |
|
| Molecular Weight (MW) | 296.32 | |
| InChIKey | LINOMUASTDIRTM-QGRHZQQGSA-N |
Deoxynivalenol (Vomitoxin) is an orally active trichothecene mycotoxin that disrupts protein synthesis by binding to eukaryotic ribosomes. This ribosomal inactivation triggers the ribotoxic stress response and activates downstream signaling pathways, including MAPK/p38. Consequent upregulation of p38-mediated gene expression promotes leukocyte apoptosis and the release of proinflammatory cytokines such as interleukin-6 (IL-6), causing gut integrity disruption and immune dysregulation. [1]
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Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
59 mg/mL
(199.1 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 59 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.