CAS No. 107316-88-1

Batch: Purity:99.97
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Demethylzeylasteral (T-96) Chemical Structure
Chemical Structure
Check the Demethylzeylasteral (T-96) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R,4aS,6aR,6aS,14aS,14bR)-9-formyl-10,11-dihydroxy-2,4a,6a,6a,14a-pentamethyl-8-oxo-1,3,4,5,6,13,14,14b-octahydropicene-2-carboxylic acid
CAS Number 107316-88-1
Molecular Formula

C29H36O6
Molecular Weight (MW) 480.59
SMILES CC12CCC(CC1C3(CCC4(C5=CC(=C(C(=C5C(=O)C=C4C3(CC2)C)C=O)O)O)C)C)(C)C(=O)O
InChIKey ZDZSFWLPCFRASW-CPISFEQASA-N

Ordering Information

Biological Activity

Demethylzeylasteral (T-96) is a natural triterpenoid isolated from Tripterygium wilfordii Hook F. that functions as an inhibitor of UDP-glucuronosyltransferase (UGT) isoforms, specifically UGT1A6 and UGT2B7. By suppressing UGT-mediated glucuronidation pathways, demethylzeylasteral modulates xenobiotic and endobiotic metabolism while exhibiting immunosuppressive properties. These inhibitory interactions alter cellular metabolic clearance and immune responses, highlighting its bioactive potential in targeted metabolic regulation. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 96 mg/mL (199.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 33 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.