CAS No. 786593-06-4

Batch: Purity:99.97
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Dehydroandrographolide Succinate Chemical Structure
Chemical Structure
Check the Dehydroandrographolide Succinate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 786593-06-4
Molecular Formula

C28H36O10
Molecular Weight (MW) 532.58
SMILES CC12CCC(C(C1CCC(=C)C2C=CC3=CCOC3=O)(C)COC(=O)CCC(=O)O)OC(=O)CCC(=O)O

Ordering Information

Biological Activity

Dehydroandrographolide succinate (DAS) is a semisynthetic diterpenoid succinate derivative derived from the medicinal plant Andrographis paniculata with broad antibacterial and antiviral activities. DAS modulates inflammatory and immune-response pathways, including suppression of NF-kB signaling, to inhibit viral replication and attenuate pathogen-induced inflammatory responses. These actions lead to decreased production of pro-inflammatory cytokines and reduced cellular pathology during infection. [1]

How to Prepare Stock Solution?

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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (187.76 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 100 mg/mL
Water Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.