CAS No. 112362-50-2
Batch:
Purity:99.95
Chemical Structure
Check the
Dalfopristin
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 112362-50-2 | |
|---|---|---|
| Molecular Formula |
C34H50N4O9S
|
|
| Molecular Weight (MW) | 690.85 | |
| SMILES | CCN(CC)CCS(=O)(=O)C1CCN2C1C(=O)OC(C(C=CC(=O)NCC=CC(=CC(CC(=O)CC3=NC(=CO3)C2=O)O)C)C)C(C)C |
Dalfopristin is a semi-synthetic streptogramin A antibiotic that targets the 50S subunit of bacterial ribosomes. It binds specifically to the peptidyl transferase center of the 23S rRNA, inducing conformational changes that block peptide bond formation and early peptide chain elongation. This action directly disrupts bacterial protein synthesis and enhances the binding affinity of streptogramin B compounds, leading to robust antibacterial activity against Gram-positive pathogens. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(144.74 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.