CAS No. 878143-33-0
Batch:
Purity:99.14
Chemical Structure
Check the
Dalasetron Mesylate Hydrate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 878143-33-0 | |
|---|---|---|
| Molecular Formula |
C19H20N2O3.CH4O3S.H2O |
|
| Molecular Weight (MW) | 438.50 |
Dolasetron mesylate hydrate is a synthetic small-molecule antagonist targeting the serotonin 5-HT3 receptor. By selectively binding to 5-HT3 receptors, the compound inhibits serotonin-mediated ion current influx and cellular membrane depolarization in sensory neurons. This receptor blockade suppresses serotonin-driven signaling pathways, downstream neuronal excitation, and vagal afferent stimulation associated with emetic reflex activation. [1]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
88 mg/mL
(200.68 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 22 mg/mL |
| Ethanol | 2 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Dalasetron Mesylate Hydrate Solubility in DMSO
- Dalasetron Mesylate Hydrate Stock Solution
- Dalasetron Mesylate Hydrate Storage
- Dalasetron Mesylate Hydrate Stability
- Dalasetron Mesylate Hydrate Molecular Weight
- Dalasetron Mesylate Hydrate Chemical Structure (2D and 3D)
- Dalasetron Mesylate Hydrate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.