CAS No. 344-25-2
Batch:
Purity:98.58
Chemical Structure
Check the
D-Proline
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 344-25-2 | |
|---|---|---|
| Molecular Formula |
C5H9NO2 |
|
| Molecular Weight (MW) | 115.13 | |
| SMILES | C1CC(NC1)C(=O)O |
D-Proline is an enantiomer of the naturally occurring amino acid L-proline, functioning as a substrate for D-amino acid metabolism enzymes including D-amino acid oxidase (DAAO). DAAO oxidizes D-proline to produce α-keto acid derivatives and hydrogen peroxide, modulating endogenous D-amino acid levels. D-Proline plays a key role in studying amino acid stereospecificity, bacterial peptidoglycan biosynthesis, and metabolic pathways involved in neurobiology and oxidative stress regulation. [1]
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 23 mg/mL |
| DMSO |
Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.