CAS No. 16816-67-4

Batch: Purity:99.57
D-Pantethine Chemical Structure
Chemical Structure
Check the D-Pantethine product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 16816-67-4
Molecular Formula

C22H42N4O8S2

Molecular Weight (MW) 554.72

Ordering Information

Biological Activity

D-Pantethine is a naturally occurring dimeric derivative of pantetheine and an intermediate precursor in coenzyme A (CoA) biosynthesis. By supplying essential precursors for CoA formation, it modulates lipid metabolism and attenuates fatty acid and cholesterol biosynthesis pathways in hepatocytes. This suppression of lipid synthesis leads to reduced cellular triglyceride accumulation and altered lipid homeostasis. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.