CAS No. 5505-63-5
Batch:
Purity:99
Chemical Structure
Check the
D-Mannosamine hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 5505-63-5 | |
|---|---|---|
| Molecular Formula |
C6H14ClNO5 |
|
| Molecular Weight (MW) | 215.63 | |
| SMILES | Cl.NC(C=O)C(O)C(O)C(O)CO |
D-Mannosamine hydrochloride is an endogenous metabolite and amino sugar derivative that acts as an inhibitor of glycosylphosphatidylinositol (GPI) anchor biosynthesis. By interfering with GPI anchor precursor assembly, it disrupts the cell-surface expression and membrane trafficking of GPI-anchored proteins. This inhibition modulates downstream cellular processes including protein sorting, signal transduction, and cell-surface glycoprotein presentation in mammalian cells.
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
43 mg/mL
(199.41 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 43 mg/mL |
| Ethanol | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- D-Mannosamine hydrochloride Solubility in DMSO
- D-Mannosamine hydrochloride Stock Solution
- D-Mannosamine hydrochloride Storage
- D-Mannosamine hydrochloride Stability
- D-Mannosamine hydrochloride Molecular Weight
- D-Mannosamine hydrochloride SMILES
- D-Mannosamine hydrochloride Chemical Structure (2D and 3D)
- D-Mannosamine hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.