CAS No. 526-95-4

Batch: Purity:
D-Gluconic acid Chemical Structure
Chemical Structure
Check the D-Gluconic acid product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name (2R,3S,4R,5R)-2,3,4,5,6-pentahydroxyhexanoic acid
CAS Number 526-95-4
Molecular Formula

C6H12O7

Molecular Weight (MW) 196.16
SMILES OCC(O)C(O)C(O)C(O)C(O)=O
InChIKey RGHNJXZEOKUKBD-SQOUGZDYSA-N

Ordering Information

Biological Activity

D-Gluconic acid is an organic acid compound that functions as an antifungal agent. It exerts its biological effects by altering cellular pH homeostasis and disrupting fungal cell membrane integrity. This disruption impairs nutrient transport and inhibits metabolic pathway functions within fungal pathogens, leading to the inhibition of fungal cell growth and survival. Consequently, D-Gluconic acid suppresses fungal proliferation across various strains. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 100 mg/mL (509.78 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 100 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.