CAS No. 57-48-7

Batch: Purity:98.55
D-Fructose Chemical Structure
Chemical Structure
Check the D-Fructose product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 57-48-7
Molecular Formula

C6H12O6

Molecular Weight (MW) 180.16

Ordering Information

Biological Activity

D-Fructose is a naturally occurring dietary monosaccharide that serves as a primary energy substrate and carbon source in cellular metabolism. Upon uptake through hexose transporters such as GLUT5, D-fructose is phosphorylated by ketohexokinase to fructose-1-phosphate, bypassing key regulatory steps of glycolysis. Metabolic flux through hepatic fructolysis promotes lipogenesis, glycogen synthesis, and altered intracellular energy status, driving downstream metabolic signaling pathways. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 36 mg/mL (199.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 36 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.