CAS No. 38099-82-0

Batch: Purity:99.03
Check CoA
D-Fructose-1,6-diphosphate trisodium salt octahydrate Chemical Structure
Chemical Structure
Check the D-Fructose-1,6-diphosphate trisodium salt octahydrate product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name trisodium;[(2R,3R,4S)-2,3,4-trihydroxy-6-[hydroxy(oxido)phosphoryl]oxy-5-oxohexyl] phosphate
CAS Number 38099-82-0
Molecular Formula

C6H11Na3O12P2
Molecular Weight (MW) 406.06
SMILES C(C(C(C(C(=O)COP(=O)([O-])[O-])O)O)O)OP(=O)(O)[O-].[Na+].[Na+].[Na+]
InChIKey CEHGLSKJDFICTB-PWVOXRODSA-K

Ordering Information

Biological Activity

D-Fructose-1,6-diphosphate trisodium salt octahydrate is an endogenous glycolytic intermediate and allosteric activator of pyruvate kinase M2 (PKM2). It serves as a precursor for glyceraldehyde 3-phosphate and dihydroxyacetone phosphate within the glycolysis pathway. By binding to PKM2, it promotes enzyme activation and regulates glycolytic flux, supporting cellular ATP generation and metabolic homeostasis. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
🧮 Molarity Calculator

Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 100 mg/mL
DMSO Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

Jump to

Note: Technical data last updated: Sep 1, 2026.