CAS No. 7326-19-4
Batch:
Purity:99.82
Chemical Structure
Check the
D-3-Phenyllactic acid
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 7326-19-4 | |
|---|---|---|
| Molecular Formula |
C9H10O3 |
|
| Molecular Weight (MW) | 166.17 | |
| SMILES | C1=CC=C(C=C1)CC(C(=O)O)O |
D-3-Phenyllactic acid is an endogenous metabolite and lactic acid bacteria product that acts as a selective agonist of hydroxycarboxylic acid receptor 3 (HCA3/GPR109B). Activation of HCA3 triggers Gi protein-dependent signaling, inhibiting adenylyl cyclase and reducing intracellular cAMP concentrations. This signaling cascade modulates immune cell functions, suppressing lipolysis and regulating inflammatory responses in human monocytes.
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Concentration
Volume
Mass
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|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
33 mg/mL
(198.59 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.