CAS No. 69-74-9
Batch:
Purity:98
Chemical Structure
Check the
Cytarabine hydrochloride
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| CAS Number | 69-74-9 | |
|---|---|---|
| Molecular Formula |
C9H13N3O5.HCl |
|
| Molecular Weight (MW) | 279.68 | |
| SMILES | C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)O.Cl |
Cytarabine hydrochloride is a pyrimidine nucleoside analog antimetabolite that functions as a DNA synthesis inhibitor. Upon intracellular conversion to its active triphosphate form, it competes with deoxycytidine triphosphate for incorporation into nuclear DNA. This incorporation inhibits DNA polymerase activity and arrests DNA chain elongation, leading to cell cycle arrest at the S-phase and induction of apoptotic cell death in leukemic cells. [1][2]
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
55 mg/mL
(196.65 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
- Cytarabine hydrochloride Clinical Trials
- Cytarabine hydrochloride Solubility in DMSO
- Cytarabine hydrochloride Stock Solution
- Cytarabine hydrochloride Storage
- Cytarabine hydrochloride Stability
- Cytarabine hydrochloride Molecular Weight
- Cytarabine hydrochloride SMILES
- Cytarabine hydrochloride Chemical Structure (2D and 3D)
- Cytarabine hydrochloride SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.