CAS No. 56-17-7

Batch: Purity:99.28
Cystamine dihydrochloride Chemical Structure
Chemical Structure
Check the Cystamine dihydrochloride product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 56-17-7
Molecular Formula

C4H12N2S2.2HCl
 

Molecular Weight (MW) 225.2
SMILES C(CSSCCN)N.Cl.Cl

Ordering Information

Biological Activity

Cystamine dihydrochloride is an anti-infective and radioprotective agent that functions as a transglutaminase inhibitor and sulfhydryl enzyme modifier. It inhibits transglutaminase activity and caspase activation, modulating cross-linking pathways and cellular stress responses. Downstream, cystamine reduces abnormal protein aggregation, attenuates apoptotic cascades, and preserves mitochondrial function in preclinical models of neurodegenerative disorders and cellular injury. [1][2]

How to Prepare Stock Solution?

Concentration Volume Mass
1 mg 5 mg 10 mg
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
Water 45 mg/mL
DMSO 14 mg/mL (62.16 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Ethanol 2 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Note: Technical data last updated: Sep 1, 2026.