CAS No. 37839-81-9

Batch: Purity:99.5811
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Cyclic AMP sodium Chemical Structure
Chemical Structure
Check the Cyclic AMP sodium product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

IUPAC Name sodium (4aR,6R,7R,7aS)-6-(6-aminopurin-9-yl)-2-oxido-2-oxo-4a,6,7,7a-tetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol
CAS Number 37839-81-9
Molecular Formula

C10H12N5O6P.Na
Molecular Weight (MW) 352.20
InChIKey BXJBFCKTIWRKMQ-MCDZGGTQSA-M

Biological Activity

Cyclic AMP sodium is an endogenous cyclic nucleotide second messenger derived from adenosine triphosphate that regulates a wide range of intracellular signal transduction pathways. It primarily activates protein kinase A (PKA) and exchange proteins directly activated by cAMP (EPAC), modulating downstream gene expression, metabolism, ion channel function, and cell proliferation.

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 70 mg/mL (198.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 70 mg/mL
Ethanol Insoluble
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.