CAS No. 1594094-64-0
Batch:
Purity:99.02
Chemical Structure
Check the
CW069
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 2-[[(2S)-2-(benzylamino)-3-phenylpropanoyl]amino]-5-iodobenzoic acid | |
|---|---|---|
| CAS Number | 1594094-64-0 | |
| Molecular Formula |
C23H21IN2O3 |
|
| Molecular Weight (MW) | 500.33 | |
| SMILES | C1=CC=C(C=C1)CC(C(=O)NC2=C(C=C(C=C2)I)C(=O)O)NCC3=CC=CC=C3 | |
| InChIKey | IRDIXDXDSUBHIU-NRFANRHFSA-N |
CW069 is a selective, allosteric inhibitor of the microtubule motor protein HSET (KIFC1) with an IC50 of, displaying selectivity over KSP. By inhibiting HSET activity, CW069 impairs centrosome clustering in cancer cells harboring extra centrosomes, inducing multipolar spindle assembly, mitotic aberration, and selective cancer cell death without impacting normal cell division. [1]
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Concentration
Volume
Mass
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Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(199.86 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
Note: Technical data last updated: Sep 1, 2026.